There is mounting evidence that probiotics are beneficial to your liver probiotic liver

Increased knowledge of the relevance of the bacteria that dwell in our gut has prompted a flurry of microbiome research and driven a thriving probiotics sector. According to a new study, probiotics can boost not only gut health but also liver health. probiotic liver

“Probiotics have been examined most intensively in the setting of the gastrointestinal system,” said Bejan Saeedi, the study’s lead author and a doctorate candidate at Emory University. “This study shows that probiotics have benefits that go beyond the gastrointestinal tract. This study is unusual in that it proposes a specific chemical mechanism for eliciting these effects.”

Saeedi will present the findings at the American Society for Investigative Pathology annual meeting, which will be held April 21-25 in San Diego, as part of the 2018 Experimental Biology meeting. probiotic liver

The huge populations of microorganisms that live on and inside our bodies have been demonstrated to have a part in a variety of bodily functions that keep us healthy. Probiotics are bacteria that are consumed or administered in order to increase the number of beneficial germs in the body. probiotic liver

The probiotic Lactobacillus rhamnosus GG (also known as LGG), which is found in many over-the-counter probiotic formulations, was the subject of Saeedi and his colleagues’ research. The mice were fed LGG-laced chow for two weeks before being given a high dosage of acetaminophen. probiotic liver

By increasing the number of a type of oxygen called free radicals, a process known as oxidative stress, taking too much acetaminophen can cause catastrophic liver damage and even death. When mice were given an overdose of acetaminophen, the researchers discovered that mice who were given probiotics had less liver damage than mice who were not given probiotics. probiotic liver

“Giving mice the probiotic LGG increases the liver’s antioxidant response, preventing it from oxidative damage caused by medications like acetaminophen,” Saeedi explained. probiotic liver

The liver is a major organ for eliminating toxins from the blood and is involved in the body’s energy conversion processes. Because the liver is “downstream” in the digestion process from the gastrointestinal tract, the makeup of bacteria in the stomach could have an impact on liver function. probiotic liver

The chemical mechanism by which LGG appears to protect against oxidative liver injury has been traced by Saeedi’s colleagues in previous study. The role of a protein called Nrf2, which regulates the production of genes involved in fighting free radicals, is highlighted in this study. probiotic liver

LGG has already been demonstrated to protect mice from alcoholic liver disease and non-alcoholic fatty liver disease in other investigations. Human volunteers would be needed to definitively investigate the possible clinical benefits of LGG in people, according to Saeedi.

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