Do probiotics aid in the treatment of diarrhoea caused by an acute infection? probiotic help with diarrhea

What is the purpose of this analysis?

Acute infectious diarrhoea is a major worldwide health problem that disproportionately affects persons in low- and middle-income nations. We wanted to see if consuming probiotics can assist reduce the time it takes for symptoms to go away. We looked for studies on the use of probiotics in persons suffering from acute diarrhoea. We looked for trials in which participants’ treatments were chosen at random; these studies frequently provide trustworthy evidence.

Key Takeaways

It’s possible that probiotics have no effect on how long severe diarrhoea lasts. We don’t know if they can reduce the amount of time it takes to recover from diarrhoea. To evaluate if probiotics assist cure acute infectious diarrhoea, we need more credible information from more research.

What was the focus of the review?

Frequent bowel motions or the passage of unusually soft or watery feces are referred to as “diarrhoea.” Acute diarrhoea is caused by gut infections caused by bacteria, viruses, or parasites, and is spread most commonly by feces-contaminated water. Acute diarrhoea typically clears itself after a few days. However, in severe acute diarrhoea, the amount of water, salts, and nutrients lost from the body is significant, resulting in dehydration and even death. Acute diarrhoea treatments try to prevent or reverse dehydration, speed up recovery, and reduce the time it takes for a person to spread the virus to others. probiotic help with diarrhea

Probiotics are live bacteria and yeasts that are believed to help restore the normal balance of microorganisms in the gut (intestines) after disease or treatment has upset it. Probiotics are microorganisms that are often described as “good” or “friendly,” and they can be found in yoghurts or taken as supplements. Probiotics may assist the gut combat dangerous microorganisms that cause diarrhoea, or reduce inflammation and damage to the gut in cases of acute infectious diarrhoea. probiotic help with diarrhea

What are the review’s key findings?

We discovered 82 studies including 12,127 participants with acute diarrhoea (mainly youngsters). Only 26 studies were conducted in countries with a high frequency of deaths among adults and children (from any cause). probioticseverything.comprobiotic help with diarrhea

The effects of various types of probiotics were compared to the effects of no extra therapy or a placebo (dummy) treatment in these investigations. We were particularly interested in:

• how many persons had diarrhoea for more than 48 hours; and 

• how long diarrhoea symptoms lasted on average.

There were numerous variances in the concept and execution of these research. Many different probiotics were tried in studies that employed varied definitions of “acute diarrhoea” and “the end of diarrhoea symptoms.” As a result, we were unable to include the findings of all studies in our analysis. probioticseverything.comprobiotic help with diarrhea

We found no change in the number of children who had diarrhoea for more than 48 hours when they were given a probiotic vs a placebo or no further treatment (two studies in high-income countries; 1770 children). We don’t know whether consuming probiotics affects the amount of time diarrhoea symptoms last (six studies; 3058 people). Participants’ age, dietary and socioeconomic level, area, or rotavirus infection, as well as whether they were receiving antibiotics or zinc supplements, had no effect on the results. probioticseverything.comprobiotic help with diarrhea

It’s possible that taking probiotics has no effect on:

• the number of people who had diarrhoea for more than 14 days (nine studies; 2928 people); 

•the number of people who were admitted to the hospital with diarrhoea (nine studies; 2928 people) (six studies; 2283 people). probioticseverything.comprobiotic help with diarrhea

It was unclear whether probiotics reduced hospitalization time when compared to a placebo or no additional treatment (24 studies; 4056 people). Few studies have found any negative side effects with probiotics, and no major side effects have been observed among probiotic users.

How trustworthy are these findings?

Previous editions of this evaluation drew conclusions from a slew of minor studies in the field and concluded that there was an effect. probioticseverything.comprobiotic help with diarrhea

This new study reveals that there is publication bias in this field, with tiny studies having a favorable effect being more likely to be published, skewing the results. This is taken into account in this new study. probioticseverything.comprobiotic help with diarrhea

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