Exploration of the mechanism of probiotics in preventing and treating constipation probiotics with antibiotics

Improving the intestinal microenvironment to promote defecation Several studies have found that the relative proportion of intestinal flora in constipated patients has changed compared with healthy people. A fecal study of 22 constipated children and 20 healthy children found that there was no difference in the total number of aerobic and anaerobic bacteria, but the number of Clostridium and Bifidobacterium in the feces of constipated children was higher than that of healthy children. Statistical significance: The number of some bacteria such as Enterococcus and fungi decreased. However, compared with healthy people, the difference was not statistically significant. Wang Jicheng et al. 127 analyzed feces of 43 constipated patients and 9 healthy people. The constipation patients were 6.1lgcfu/g ± 0.92lgcfu/g, and the constipated patients were given Bifidobacterium animalis (Banimalis V9) powder 1.0 x 10cfu/d for 21 days continuously. The number of Rod and Enterococcus decreased in different degrees. The relative proportion of intestinal bacteria changed in constipation patients. It can be considered as a kind of ecological imbalance. Does constipation lead to changes in the proportion of intestinal flora or changes in the proportion of bacteria? One of the causes of constipation is for further study. probiotics with antibiotics probiotics with antibiotics probiotics with antibiotics
Shortening the colonic transit time and promoting the rapid passage of food debris through the colon Studies have shown that oral intake of a certain amount of Bifidobacterium lactis (Blac tis DN-173010) can promote the passage of intestinal contents through the colon and shorten the colon in both healthy people and patients with functional constipation. Transit Time 29 A double randomized controlled study of 72 healthy adults (21-42 years) examining colonic transit time with contrast media. Results showed a 21% reduction in overall colonic transit time after treatment with live BanimalisDN-173010 The transit time of the sigmoid colon was shortened by 39%, especially in women (the bacteria after heating had no effect). The placebo group (n=34) had shorter intestinal transit time and defecation time compared to high-dose (n=33) and low-dose Bifidobacterium most nonacidic ingestors (n=33), and probiotics promoted bowel movements and shortened the colon The mechanism of transit time is unclear, but it may be related to the production of lactic acid, acetic acid and short-chain fatty acids by probiotics and the action of short-chain fatty acids on intestinal nerves to stimulate peristalsis. probiotics with antibiotics probiotics with antibiotics probiotics with antibiotics

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